Postdoc in Signal Transduction at University of Dundee -Cell Biology, Biochemistry, Molecular Biology-Apply

Description & Details:  The Sapkota lab is seeking a postdoctoral researcher to undertake research in collaboration with one of the leading pharmaceutical companies supporting the Division of Signal Transduction Therapy (DSTT). The DSTT facilitates collaborations between the world’s major pharmaceutical companies (Boehringer Ingelheim, GlaxoSmithKline, and Merck-Serono) and leading Dundee-based researchers with a proven track record of achievement in understanding and exploiting the fundamental molecular causes of human disease in the fields of cancer, immune-regulation, neurodegeneration and hypertension resulting from disruptions in protein phosphorylation, ubiquitylation and other signalling networks.

The successful applicant will be based within the Sapkota lab in Dundee at the MRC Protein Phosphorylation and Ubiquitylation Unit (http://www.ppu.mrc.ac.uk/). The applicant will employ cutting-edge CRISPR/Cas9 genome editing and mass-spectrometric technologies as well as state-of-the-art blend of molecular, biochemical and cell biology methodologies to address disease-relevant research questions.

Candidate requirements:

• PhD with outstanding academic track record and at least one first authored publication in an internationally recognised peer-reviewed journal.
• Strong background in Cell Biology, Biochemistry, Molecular Biology and Signal Transduction is desired.
• Experience and strong interest in signal transduction research and how disruptions of these pathways are linked to human disease.
• Capable of working in a team, but able to plan and work independently.
• Excellent communication skills and knowledge of the English language are essential.
• The candidate should have ambitions to become a successful independent researcher either in academia or the pharmaceutical/biotechnology industry.

The position is available for 2 years with possibility of further 2 year extension.

The position will be on the University of Dundee Grade 7 scale points 29-31 only (£30,738 – £32,600 per annum).

Appointment as a Postdoctoral Research Assistant on the Grade 7 salary scale is dependent upon you having been awarded a PhD.  An appointment may be considered if you are shortly expected to be awarded a PhD. The initial appointment will be made as a Research Assistant on the Training Grade 7 salary scale (Spinal Point 28, £29,847).

MRC Protein Phosphorylation and Ubiquitylation Unit (PPU):

The MRC-PPU and the one of the world’s most renowned centres for research on protein phosphorylation and ubiquitylation (http://www.ppu.mrc.ac.uk/). Many world leading researchers in the field of signal transduction have trained within the MRC-PPU. The major aims of the MRC-PPU are to advance understanding of the role of protein phosphorylation and ubiquitylation in cell regulation and human disease, to facilitate the development of drugs to treat diseases caused by abnormalities in phosphorylation, to generate reagents and improve technologies. A key remit of the MRC-PPU is to train the next generation of scientists who will advance our understanding in this crucial area of medical research.

View More Details