Postdoc in cancer at University of Dundee, UK-PhD biochemistry, molecular biology, cellular biology-Apply

Description & Details: Applications are invited for a postdoctoral position to work with Dr. Gopal Sapkota to investigate the molecular function and regulation of PAWS1/FAM83G in cells and cancer. Following the discovery of PAWS1 (Protein Associated With Smad1) as a player in the BMP pathway in the lab, we have established key roles for PAWS1 in transcription, cell migration and cancer. This project aims to uncover the molecular mechanisms of PAWS1 function in cells and understand how PAWS1 itself is regulated. The project will exploit state-of-the-art technologies including CRISPR/CAS9 genome-editing, mass spectrometry, fluorescence microscopy as well as other molecular, cellular and biochemical techniques.

MRC Protein Phosphorylation and Ubiquitylation Unit (PPU):

The successful applicant will have the opportunity to work in an exciting and collaborative research environment, equipped to the highest international standards. Major aims of the MRC-PPU are to advance understanding of the role of protein phosphorylation and ubiquitylation in cell regulation and human disease; to facilitate the development of drugs to treat diseases caused by abnormalities in phosphorylation; and to generate reagents and improve technologies. Another key remit of the MRC-PPU is to train the next generation of scientists who will advance our understanding in this crucial area of medical research. The MRC-PPU is in a beautiful location overlooking the estuary of the River Tay and embedded within the School of Life Sciences at the University of Dundee, which is one of the premier Life Sciences research Centres in the world.

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